2100306-80-5

2100306-80-5 structure
2100306-80-5 structure
  • Name: Hydroxy-PEG5-C2-methyl ester
  • Chemical Name: Hydroxy-PEG5-methyl ester
  • CAS Number: 2100306-80-5
  • Molecular Formula: C14H28O8
  • Molecular Weight: 440.53
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-03 14:46:14
  • Modify Date: 2024-01-12 21:03:29
  • Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Hydroxy-PEG5-methyl ester
Synonyms MFCD30730370
Description Hydroxy-PEG5-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C14H28O8
Molecular Weight 440.53