78510-31-3

78510-31-3 structure

Name: PSB 069
Chemical Name: sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
CAS Number: 78510-31-3
Molecular Formula: C₂₀H₁₂ClN₂NaO₅S
Molecular Weight: 450.82700
Catalog: Research Areas Cancer
Create Date: 2017-01-06 18:28:15
Modify Date: 2024-01-22 15:35:40
PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].

Name	sodium 1-amino-4-(4-chlorophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate

Description	PSB069 bearing a p-chlorophenylamino residue is a potent, well-tolerated and nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
Target	Ki: 16~18 μM (NTPDases1, 2, 3)[1]
In Vitro	PSB069 is a nonselective NTPDases1, 2, 3 inhibitor(Ki=16~18 μM)[1].
References	[1]. Baqi Y, et al. Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases). Purinergic Signal. 2009;5(1):91-106.