1190-14-3
1190-14-3 structure
- Name: 4-Bromobutylphosphonic acid
- Chemical Name: (4-bromobutyl)phosphonic acid
- CAS Number: 1190-14-3
- Molecular Formula: C4H10BrO3P
- Molecular Weight: 216.99800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-07-27 03:29:04
- Modify Date: 2024-01-12 17:51:12
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4-Bromobutylphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | (4-bromobutyl)phosphonic acid |
|---|---|
| Synonyms |
.(4-bromo-butyl)-phosphonic acid
.4-Brom-butanphosphonsaeure 4-bromobutylphosphonic acid .4-Brom-butan-phosphonsaeure-(1) |
| Description | 4-Bromobutylphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Melting Point | 129 °C |
|---|---|
| Molecular Formula | C4H10BrO3P |
| Molecular Weight | 216.99800 |
| Exact Mass | 215.95500 |
| PSA | 67.34000 |
| LogP | 1.33920 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
