Top Suppliers:I want be here
Related CAS#:
123-33-1 14628-35-4
2398483-97-9 28382-15-2
61167-10-0 15456-83-4
5716-15-4 2797-52-6
6216-73-5 1430102-87-6
2227792-07-4 1158522-08-7
2228970-59-8 2408938-23-6
940364-43-2 2228241-66-3
134104-43-1 131615-57-1
2171441-45-3 6906-52-1

123-33-1

123-33-1 structure
123-33-1 structure
  • Name: Maleic hydrazide
  • Chemical Name: maleic hydrazide
  • CAS Number: 123-33-1
  • Molecular Formula: C4H4N2O2
  • Molecular Weight: 112.087
  • Catalog: Chemical pesticide Plant Growth Regulator
  • Create Date: 2018-04-05 08:00:00
  • Modify Date: 2024-01-02 17:30:12
  • Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].
Name maleic hydrazide
Synonyms Vondalhyd
Yadi
MG-T
3(2H)-Pyridazinone, 6-hydroxy-
cis-Butenedioic acid hydrazide
MH-30
EINECS 204-619-9
3,6-Dihydroxypyridazine
3,6-dioxo-1,2,3,6-tetrahydropyridazine
1,2-Dihydro-3,6-pyridazinedione
T6VMMVJ
1,2-dihydro 3,6-pyridazinedione
pyridazine-3,6-diol
gotax
1,2,3,6-Tetrahydro-3,6-dioxopyridazine
MFCD00006665
1,2-dihydropyridazine-3,6-dione
Bos MH
KMH
6-hydroxy-2H-pyridazin-3-one
Fazor
Maleic hydrazine
T6NMVJ FQ
Yake
Hydrazide maleique
1,2-Dihydro-3,6-pyridazinedione,3,6-Dihydroxypyridazine,3,6-Pyridazinediol
Maleic Hydrazide
MH-40
3,6-Pyridazinedione, 1,2-dihydro-
mAh
3,6-Pyridazinediol
mH
Maleic acid cyclic hydrazide
T6NNJ CQ FQ
Maleic Acid Hydrazide
Description Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins[1][2].
Related Catalog
In Vitro Maleic hydrazide is used in agriculture-in despite its known effect as a mutagenic and clastogenic agent. Maleic hydrazide had lower IC50 values for all cell lines compared to Ethephon. Maleic hydrazide also showed least cytotoxicity on Vero cells, followed by Hep2 and HepG2 cells[3].
In Vivo Maleic hydrazide has a low acute toxicity by oral, dermal, and inhalation routes of exposure[3].
References

[1]. Venezian A, et al. The Influence of the Plant Growth Regulator Maleic Hydrazide on Egyptian Broomrape Early Developmental Stages and Its Control Efficacy in Tomato under Greenhouse and Field Conditions. Front Plant Sci. 2017;8:691. Published 2017 May 16.

[2]. Swietlińska Z, et al. Cytotoxic effects of maleic hydrazide. Mutat Res. 1978;55(1):15-30.

[3]. Yurdakok B, et al. Cytotoxic effects of etephon and maleic hydrazide in Vero, Hep2, HepG2 cells. Drug Chem Toxicol. 2014;37(4):459-465.
Density 1.5±0.1 g/cm3
Boiling Point 477.2±25.0 °C at 760 mmHg
Melting Point 306-308 ºC
Molecular Formula C4H4N2O2
Molecular Weight 112.087
Flash Point 242.4±23.2 °C
Exact Mass 112.027275
PSA 65.72000
LogP -0.14
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.640
Water Solubility 6 g/L

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR5950000
CHEMICAL NAME :
3,6-Pyridazinedione, 1,2-dihydro-
CAS REGISTRY NUMBER :
123-33-1
LAST UPDATED :
199701
DATA ITEMS CITED :
38
MOLECULAR FORMULA :
C4-H4-N2-O2
MOLECULAR WEIGHT :
112.10
WISWESSER LINE NOTATION :
T6VMMVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>20 gm/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - duck
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg/4W-I
TOXIC EFFECTS :
Endocrine - changes in thymus weight Immunological Including Allergic - increase in humoral immune response
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2600 mg/kg/65W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
Specific locus test
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Sex chromosome loss and nondisjunction
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
100 ug/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,1,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,173,1974 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,173,1974 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84780 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 124 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84780 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1440 (estimated)
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H315-H319-H335-H341
Precautionary Statements P261-P281-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R36/37/38;R40
Safety Phrases S26-S36-S45-S36/37/39
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS UR5950000
HS Code 2928000090
108-31-6 structure

108-31-6

~92%

123-33-1 structure

123-33-1

Literature: Edelmann, Michael J.; Raimundo, Jean-Manuel; Utesch, Nils F.; Diederich, Francois; Boudon, Corinne; Gisselbrecht, Jean-Paul; Gross, Maurice Helvetica Chimica Acta, 2002 , vol. 85, # 7 p. 2195 - 2213
5343-00-0 structure

5343-00-0

~%

123-33-1 structure

123-33-1

Literature: Journal of the American Chemical Society, , vol. 80, p. 3790
110-16-7 structure

110-16-7

~%

123-33-1 structure

123-33-1

Literature: Journal of the American Chemical Society, , vol. 80, p. 3790
18259-51-3 structure

18259-51-3

~%

123-33-1 structure

123-33-1

Literature: Chemical and Pharmaceutical Bulletin, , vol. 7, p. 938,940
108-31-6 structure

108-31-6

7803-57-8 structure

7803-57-8

64-19-7 structure

64-19-7

~%

123-33-1 structure

123-33-1

Literature: Journal of the American Chemical Society, , vol. 80, p. 3790
HS Code 2933990011
Summary 2933990011 o,o-diethyl o-quinoxalin-2-yl phosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Chemsrc provides CAS#:123-33-1 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 123-33-1 | Chemsrc address: https://www.chemsrc.com/en/baike/1090894.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved