18865-48-0

18865-48-0 structure

Name: Actinomycin X2
Chemical Name: actinomycin v
CAS Number: 18865-48-0
Molecular Formula: C₆₂H₈₄N₁₂O₁₇
Molecular Weight: 1269.40000
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-09-13 10:46:27
Modify Date: 2024-01-11 15:27:09
Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1].

Name	actinomycin v
Synonyms	5'-Deoxy(Methylthio-d3)adenosine 3h-phenoxazine,actinomycindderiv. [A3-(4-oxo-L-proline)]-actinomycin-D 5'-S-(Methyl-d3)thioadenosine 3a-(4-oxo-l-proline)-actinomycin 5'-(Methylthio-d3)adenosine actinomycin-V ACTINOMYCIN X2

Description	Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp., shows strong inhibition of MRSA with a minimum inhibitory concentration (MIC) value of 0.25 μg/mL. Actinomycin X2 can be used for cancer and bacterial infection[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Zhiyu Chen, et al. Anti-MRSA Activity of Actinomycin X 2 and Collismycin A Produced by Streptomyces globisporusWA5-2-37 From the Intestinal Tract of American Cockroach ( Periplaneta americana). Front Microbiol. 2020 Apr 7;11:555.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 38,1625,1985

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,427,1977

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(2),48,1980