475115-35-6

475115-35-6 structure

Name: Galnon
Chemical Name: Galnon,3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide
CAS Number: 475115-35-6
Molecular Formula: C₄₀H₄₆N₄O₆
Molecular Weight: 678.82
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2019-01-12 20:18:37
Modify Date: 2024-01-07 16:02:14
Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].

Name	Galnon,3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide
Synonyms	GALNON FMoc-b-cyclohexyl-Ala-Lys-AMC VU 590 dihydrochloride FMoc-Cha-Lys-AMC

Description	Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
References	[1]. Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. [2]. Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20.

WGK Germany	3