528851-31-2

528851-31-2 structure
528851-31-2 structure
  • Name: desethylene ciprofloxacin, hydrochloride
  • Chemical Name: 7-(2-aminoethylamino)-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid,hydrochloride
  • CAS Number: 528851-31-2
  • Molecular Formula: C15H17ClFN3O3
  • Molecular Weight: 341.77
  • Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
  • Create Date: 2016-11-29 06:39:28
  • Modify Date: 2024-01-08 17:00:38
  • Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity[1].

Name 7-(2-aminoethylamino)-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid,hydrochloride
Synonyms Enrofloxacin Imp. G (EP),HCl
Desethylene Ciprofloxacin,Hydrochloride
7-[(2-amino-ethyl)amino]-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-quinoline-3-carboxylic acid hydrochloride
BAY-r 3964,M1-Ciprofloxacin,7-[(2-Aminoethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid
Description Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity[1].
Related Catalog
References

[1]. Šíma M, et al. Factors Affecting the Metabolic Conversion of Ciprofloxacin and Exposure to Its Main Active Metabolites in Critically Ill Patients: Population Pharmacokinetic Analysis of Desethylene Ciprofloxacin. Pharmaceutics. 2022 Aug 4;14(8):1627.  

Melting Point >240ºC dec.
Molecular Formula C15H17ClFN3O3
Molecular Weight 341.77
Exact Mass 341.09400
PSA 97.35000
LogP 3.11960
Storage condition -20°C Freezer, Under Inert Atmosphere
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H410
Precautionary Statements P273-P301 + P310-P501
Hazard Codes T,N
Risk Phrases 25-50/53
Safety Phrases 45-60-61
RIDADR UN 2811 6.1 / PGIII

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528851-31-2 structure

528851-31-2

Literature: WO2004/101590 A1, ; Page 32-33 ;
Precursor  2

DownStream  0