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81069-02-5

81069-02-5 structure
81069-02-5 structure
  • Name: DTSSP Crosslinker
  • Chemical Name: 3,3'-Dithiobis(sulfosuccinimidylpropionate)
  • CAS Number: 81069-02-5
  • Molecular Formula: C14H16N2O14S4
  • Molecular Weight: 564.54200
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-12-29 19:18:03
  • Modify Date: 2024-01-11 16:38:49
  • DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name 3,3'-Dithiobis(sulfosuccinimidylpropionate)
Synonyms N,N'-dioctyl-3,3'-disulfanediyl-bis-propionamide
N,N'-Bis-n-octyl-3,3'-dithiopropionamide
3,3'-disulfanediylbis(N-octylpropanamide)
3,3-dithiobis(sulfosuccinimidyl propionate)
N,N'-di-n-octyl-3,3'-dithiodipropionamide
N,N'-Di-n-octyl-3,3'-dithiodipropionamid
Propanamide,3,3'-dithiobis[N-octyl
(SCH2CH2CONHC8H17)2
3,3'-dithiobis(N-octylpropionamide)
Description DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Density 1.94
Molecular Formula C14H16N2O14S4
Molecular Weight 564.54200
Exact Mass 563.94800
PSA 303.46000
LogP 0.13240
Index of Refraction 1.693
Hazard Codes Xi
Safety Phrases 26-36