62802-77-1
62802-77-1 structure
- Name: VEGFR-2-IN-29
- Chemical Name: 3-nitro-N-quinolin-8-ylbenzamide
- CAS Number: 62802-77-1
- Molecular Formula: C16H11N3O3
- Molecular Weight: 293.27700
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
- Create Date: 2017-07-22 11:01:29
- Modify Date: 2024-01-10 12:19:49
-
VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1].
| Name | 3-nitro-N-quinolin-8-ylbenzamide |
|---|---|
| Synonyms |
3-Nitro-N-(8-chinolinyl)benzamid
3-Nitro-N-quinolin-8-yl-benzamide |
| Description | VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
VEGFR-2:16.5 nM (IC50) |
| In Vitro | VEGFR-2-IN-29 (Compound 5) (72 h) inhibits HUVEC proliferation[1]. Cell Proliferation Assay[1] Cell Line: HUVEC Concentration: Incubation Time: 72 h Result: Showed inhibition with IC50s of 15.8 nM and 210 nM against VEGF- and bFGF-induced HUVEC proliferation. |
| References |
| Molecular Formula | C16H11N3O3 |
|---|---|
| Molecular Weight | 293.27700 |
| Exact Mass | 293.08000 |
| PSA | 91.30000 |
| LogP | 4.30250 |
