2439096-06-5

2439096-06-5 structure

Name: VEGFR-2-IN-26
Chemical Name: VEGFR-2-IN-26
CAS Number: 2439096-06-5
Molecular Formula: C₂₄H₁₉F₃N₆O₂
Molecular Weight: 480.44
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2022-08-22 17:49:22
Modify Date: 2024-01-02 19:53:26
VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].

Name	VEGFR-2-IN-26

Description	VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR-2:15.5 nM (IC50)
References	[1]. Hadi SRAE, et al. Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors. Bioorg Chem. 2020 Aug;101:103961.

Molecular Formula	C₂₄H₁₉F₃N₆O₂
Molecular Weight	480.44