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6018-19-5

6018-19-5 structure
6018-19-5 structure

Name Sodium 4-aminosalicylate dihydrate
Synonyms Sodium 4-Aminosalicylate
EINECS 205-091-2
4-amino-2-hydroxybenzoic acid sodium salt dihydrate
Benzoic acid, 4-amino-2-hydroxy-, monosodium salt, dihydrate
Benzoic acid, 4-amino-2-hydroxy-, sodium salt, hydrate (1:1:2)
4-Aminosalicylic acid sodium salt dihydrate
AMINOSALICYLATE SODIUM,DIHYDRATE
4-AMINOSALICYLIC ACID,NA SALT
Sodium 4-amino-2-hydroxybenzoate dihydrate
4-AMINOSALICYLIC ACID SODIUM SALT 2-HYDRATE
4-Amino-2-hydroxy-benzoesaeure,Natrium-Salz
4-AMINOSALICYLIC ACID SODIUM DIHYDRATE
sodium p-aminosalicylate dihydrate
SODIUM AMINOSALICYLA
4-amino-2-hydroxy-benzoic acid,sodium-salt
4-amino-salicylic acid sodium salt
AMINOSALICYLATESODIUM,DIHYDRATE,USP
UNII-S38B9W6AXW
PAS-NA 2H2O
Sodium 4-aminosalicy
MFCD00151044
Sodium 4-amino-2-hydroxybenzoate hydrate (1:1:2)
Boiling Point 380.8ºC at 760 mmHg
Melting Point 250 °C
Molecular Formula C7H10NNaO5
Molecular Weight 211.148
Flash Point 184.1ºC
Exact Mass 211.045670
PSA 104.84000
Water Solubility soluble
Name: 4-Aminosalicylic Acid Sodium Salt Dihydrate 98% Material Safety Data Sheet
Synonym: PAS; 4-Amino-2-Hydroxybenzoic Acid
CAS: 6018-19-5
Section 1 - Chemical Product MSDS Name:4-Aminosalicylic Acid Sodium Salt Dihydrate 98% Material Safety Data Sheet
Synonym:PAS; 4-Amino-2-Hydroxybenzoic Acid

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
6018-19-5 4-Aminosalicylic Acid Sodium Salt Dihy 98% unlisted
Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Light sensitive.Air sensitive.
Potential Health Effects
Eye:
Causes eye irritation. May cause chemical conjunctivitis.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage.
Inhalation:
Causes respiratory tract irritation. Can produce delayed pulmonary edema.
Chronic:
Effects may be delayed. Chronic exposure may cause liver damage.

Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Place under an inert atmosphere.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light. Handle under an inert atmosphere. Store protected from air.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from light. Store under an inert atmosphere.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 6018-19-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Crystals
Color: white
Odor: Odorless or slight acetous
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 250 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 250 deg C
Solubility in water: soluble
Specific Gravity/Density: >1.0
Molecular Formula: C7H6NO3Na.2H2O
Molecular Weight: 211.15

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, light, dust generation, exposure to air, excess heat.
Incompatibilities with Other Materials:
Air, strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 6018-19-5 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
4-Aminosalicylic Acid Sodium Salt Dihydrate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 6018-19-5: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 6018-19-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6018-19-5 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918219000
HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%