863394-07-4

863394-07-4 structure

Name: 3-(Methylselanyl)-L-alanine hydrochloride (1:1)
Chemical Name: (2R)-2-amino-3-methylselanylpropanoic acid,hydrochloride
CAS Number: 863394-07-4
Molecular Formula: C₄H₁₀ClNO₂Se
Molecular Weight: 218.54
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2016-02-05 10:18:45
Modify Date: 2024-01-05 00:43:14
Se-Methylselenocysteine hydrochloride, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine hydrochloride is orally bioavailable, and induces apoptosis[1][2].

Name	(2R)-2-amino-3-methylselanylpropanoic acid,hydrochloride
Synonyms	Se-MSC M 6680 L-Alanine, 3-(methylseleno)-, hydrochloride (1:1) 3-(Methylselanyl)-L-alanine hydrochloride (1:1)

Description	Se-Methylselenocysteine hydrochloride, a precursor of Methylselenol, has potent cancer chemopreventive activity and anti-oxidant activity. Se-Methylselenocysteine hydrochloride is orally bioavailable, and induces apoptosis[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> Beta-secretase
References	[1]. Yeo JK, et al. Se-methylselenocysteine induces apoptosis through caspase activation and Bax cleavage mediated by calpain in SKOV-3 ovarian cancer cells. Cancer Lett. 2002 Aug 8;182(1):83-92. [2]. Cao S, et al. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models. Br J Cancer. 2014 Apr 2;110(7):1733-43. [3]. Xie Y, et al. Se-Methylselenocysteine Ameliorates Neuropathology and Cognitive Deficits by Attenuating Oxidative Stress and Metal Dyshomeostasis in Alzheimer Model Mice. Mol Nutr Food Res. 2018 Jun;62(12):e1800107.

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%