907577-50-8

907577-50-8 structure

Name: m-PEG16-NH2
Chemical Name: MeO-16eg-NH2
CAS Number: 907577-50-8
Molecular Formula: C₃₃H₆₉NO₁₆
Molecular Weight: 735.89800
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-05-14 08:00:00
Modify Date: 2024-01-12 09:17:36
m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	MeO-16eg-NH2
Synonyms	mPEG16-NH2

Description	m-PEG16-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.