94825-74-8
94825-74-8 structure
- Name: 3-O-Methyl-N-acetyl-D-glucosamine
- Chemical Name: N-[(3R,4R,5S,6R)-2,5-dihydroxy-6-(hydroxymethyl)-4-methoxyoxan-3-yl]acetamide
- CAS Number: 94825-74-8
- Molecular Formula: C9H17NO6
- Molecular Weight: 235.23400
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-12-25 15:10:47
- Modify Date: 2024-01-09 17:43:57
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3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine[1].
| Name | N-[(3R,4R,5S,6R)-2,5-dihydroxy-6-(hydroxymethyl)-4-methoxyoxan-3-yl]acetamide |
|---|---|
| Synonyms |
3-O-Methyl-N-acetyl-D-glucosamine
N-Acetyl-3-O-methyl-D-glucosamine 2-Acetamido-2-deoxy-3-O-methyl-D-glucopyranose 3-O-OME-GLCNAC 2-Acetylamino-O3-methyl-2-desoxy-D-glucose 2-acetylamino-O3-methyl-2-deoxy-D-glucose 2-Acetamido-2-deoxy-3-O-methyl-D-glucose 2-ACETAMIDO-2-DEOXY-3-O-METHYL-D-GLUCOPYRANOSE,OFF-WHITE SOLID 3-OME-GLCNAC |
| Description | 3-O-Methyl-N-acetyl-D-glucosamine is a potent inhibitor of N-acetylglucosamine kinase. 3-O-Methyl-N-acetyl-D-glucosamine potently inhibits glucose phosphorylation by N-acetylglucosamine kinase whereas glucokinase is not at all affected by this hexosamine[1]. |
|---|---|
| Related Catalog | |
| Target |
N-acetylglucosamine kinase[1] |
| References |
| Density | 1.368g/cm3 |
|---|---|
| Boiling Point | 542.355ºC at 760 mmHg |
| Melting Point | 189-191ºC |
| Molecular Formula | C9H17NO6 |
| Molecular Weight | 235.23400 |
| Flash Point | 281.806ºC |
| Exact Mass | 235.10600 |
| PSA | 108.25000 |
| Index of Refraction | 1.534 |
|
~%
94825-74-8 |
| Literature: Jeanloz Advances in Carbohydrate Chemistry, 1958 , vol. 13, p. 189,194,206 Journal of Organic Chemistry, 1961 , vol. 26, p. 905,907 Full Text View citing articles Show Details Kuhn et al. Chemische Berichte, 1954 , vol. 87, p. 1138,1141 |
| Precursor 1 | |
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| DownStream 0 | |