132746-60-2

132746-60-2 structure

Name: CP-96345
Chemical Name: (2S,3S)-2-benzhydryl-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
CAS Number: 132746-60-2
Molecular Formula: C₂₈H₃₂N₂O
Molecular Weight: 412.57
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2017-10-17 04:29:46
Modify Date: 2024-01-09 19:03:35
CP-96,345 is a specific, highly potent, and orally active tachykinin and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation[1].

Name	(2S,3S)-2-benzhydryl-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
Synonyms	(2S,3S)-cis-2-(Diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine CP 96,345

Description	CP-96,345 is a specific, highly potent, and orally active tachykinin and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
Target	Tachykinin, Substance P receptor[1]
References	[1]. Lembeck F, et al. The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation. Br J Pharmacol. 1992;105(3):527-530.