59143-60-1
59143-60-1 structure
- Name: Cephalosporin C zinc salt
- Chemical Name: Cephalosporin C Zinc Salt
- CAS Number: 59143-60-1
- Molecular Formula: C16H19N3O8SZn
- Molecular Weight: 478.78
- Catalog: API Synthetic anti-infective drugs Antifungal drugs
- Create Date: 2018-05-14 08:00:00
- Modify Date: 2024-01-09 11:43:47
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Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM.
| Name | Cephalosporin C Zinc Salt |
|---|---|
| Synonyms |
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(5R)-5-amino-5-carboxy-1-oxopentyl]amino]-8-oxo-, (6R,7R)-
(6R,7R)-3-(Acetoxymethyl)-7-{[(5R)-5-amino-5-carboxypentanoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cephalosporin Cephalosporin C |
| Description | Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.1 μM (SAMHD1)[1] |
| In Vitro | Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM)[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 814.7±65.0 °C at 760 mmHg |
| Melting Point | 240-242°C |
| Molecular Formula | C16H19N3O8SZn |
| Molecular Weight | 478.78 |
| Flash Point | 446.5±34.3 °C |
| LogP | -0.20 |
| Vapour Pressure | 0.0±6.3 mmHg at 25°C |
| Index of Refraction | 1.639 |
| Storage condition | 2-8°C |