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1421365-63-0

1421365-63-0 structure
1421365-63-0 structure
  • Name: CYM 50769
  • Chemical Name: cym50769
  • CAS Number: 1421365-63-0
  • Molecular Formula: C24H17ClN2O3
  • Molecular Weight: 416.86
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-04-18 12:19:59
  • Modify Date: 2024-01-12 12:55:38
  • CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1].

Name cym50769
Description CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1). CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1].
Related Catalog
Target

NPBWR1, GPR7[1]

In Vitro CYM 50769 (1 and 3 μM; 30 min) attenuates the NPW-23-induced ATDC5 cell proliferation in a dose-dependent manner[1]. Cell Proliferation Assay Cell Line: ATDC5 (exposed with 200 ng/mL NPW-23 for 24 h)[1] Concentration: 1 and 3 μM Incubation Time: 30 min Result: Attenuated the NPW-23-induced cell proliferation in a dose-dependent manner.
References

[1]. Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23(3):614-9.

Molecular Formula C24H17ClN2O3
Molecular Weight 416.86
Exact Mass 416.09300
PSA 53.35000
LogP 5.31570
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H413
RIDADR NONH for all modes of transport