GL Biochem (Shanghai) Ltd.
China
Product Name: β-Interleukin I (163-171)
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: VAL-GLN-GLY-GLU-GLU-SER-ASN-ASP-LYS
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Taiwan Oyi peptide Co. Ltd
China
Product Name: β-Interleukin I (163-171), human
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Vinnie

106021-96-9

106021-96-9 structure

Name: β-Interleukin I (163-171), human
Chemical Name: val-gln-gly-glu-glu-ser-asn-asp-lys
CAS Number: 106021-96-9
Molecular Formula: C₃₉H₆₄N₁₂O₁₉
Molecular Weight: 1004.99000
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-06-30 05:47:09
Modify Date: 2024-01-03 15:51:57
β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator. β-Interleukin I (163-171), human is not an IL-1R-binding domain of IL-1β. β-Interleukin I (163-171), human is a potent adjuvant that enhances the immune response in a variety of exptl. situations[1][3][4].

Name	val-gln-gly-glu-glu-ser-asn-asp-lys
Synonyms	β-Interleukin I (163-171)

Description	β-Interleukin I (163-171), human, an immunostimulatory fragment of human IL-1β peptide, is a T cell activator. β-Interleukin I (163-171), human is not an IL-1R-binding domain of IL-1β. β-Interleukin I (163-171), human is a potent adjuvant that enhances the immune response in a variety of exptl. situations[1][3][4].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	β-Interleukin I (163-171), human (12.5-400 μg/mL, 72 h) stimulates mouse thymocyte proliferation[6].
In Vivo	β-Interleukin I (163-171), human (50 μg, daily, a poorly immunogenic fibrosarcoma (CE-2) of BALB/c mice model) induces a consistent but limited inhibition of tumor growth[2]. β-Interleukin I (163-171), human (1 μmole/kg, i.v.) together with the T-dependent antigen SRBC increases the primary immune response against the antigen[3].
References	[1]. Nencioni L, et al. In vivo immunostimulating activity of the 163-171 peptide of human IL-1 beta. J Immunol. 1987 Aug 1;139(3):800-4. [2]. Forni G, et al. Ability of a nonapeptide of the human IL-1 beta to recruit anti-tumor reactivity in recipient mice. J Immunol. 1989 Jan 15;142(2):712-8. [3]. Boraschi D, , et al. In vivo stimulation and restoration of the immune response by the noninflammatory fragment 163-171 of human interleukin 1 beta. J Exp Med. 1988 Aug 1;168(2):675-86. [4]. Tagliabue, A., et al. (1997). Interleukin 1 and Its Synthetic Peptide 163–171 as Vaccine Adjuvants. Vaccine Design pp 167-173. [5]. Boraschi D, et al. Binding and internalization of the 163-171 fragment of human IL-1 beta. Cytokine. 1992 May;4(3):201-4. [6]. Bajpai K, et al. Immunomodulating activity of analogs of noninflammatory fragment 163-171 of human interleukin-1beta. Immunopharmacology. 1998 Jan;38(3):237-45.

Density	1.419g/cm3
Boiling Point	1682.6ºC at 760mmHg
Molecular Formula	C₃₉H₆₄N₁₂O₁₉
Molecular Weight	1004.99000
Flash Point	971.4ºC
Exact Mass	1004.44000
PSA	540.45000
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.573
Storage condition	-20°C

WGK Germany	3

106021-96-9	309247-07-2
60675-77-6	54405-27-5
39024-57-2	19361-51-4
624735-23-5	10047-33-3
67763-96-6	60748-07-4