Name | tolazoline |
---|---|
Synonyms |
Benzidazol
Tolazolin 2-benzyl-4,5-diyhdroimidazole 2-Benzyl-4,5-dihydro-1H-imidazole Priscol EINECS 200-448-9 2-(phenylmethyl)-4,5-dihydro-1H-imidazole Prefaxil 1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)- 2-benzyl-2-imidazoline tolazoline Imidalin MFCD00005182 2-Benzyl-4,5-dihydroimidazole Divascol 2-Benzylimidazoline Olitensol Priscoline |
Description | Tolazoline(NSC35110; Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.IC50 value:Target: α-adrenoceptor antagonistTolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of tolazoline is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics. |
---|---|
Related Catalog | |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 338.2±21.0 °C at 760 mmHg |
Melting Point | 66-69 °C(lit.) |
Molecular Formula | C10H12N2 |
Molecular Weight | 160.216 |
Flash Point | 158.3±22.1 °C |
Exact Mass | 160.100052 |
PSA | 24.39000 |
LogP | 2.65 |
Vapour Pressure | 0.0±0.7 mmHg at 25°C |
Index of Refraction | 1.596 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
|
Hazard Codes | Xn: Harmful; |
---|---|
Risk Phrases | R20/21/22;R36/37/38 |
Safety Phrases | S26-S28-S36/37/39-S45 |
WGK Germany | 3 |
RTECS | NJ1925000 |
HS Code | 2933290090 |
Precursor 10 | |
---|---|
DownStream 3 | |
HS Code | 2933290090 |
---|---|
Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |