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153870-20-3

153870-20-3 structure
153870-20-3 structure
  • Name: S-acetyl-PEG3-alcohol
  • Chemical Name: S-acetyl-triethylene glycol
  • CAS Number: 153870-20-3
  • Molecular Formula: C8H16O4S
  • Molecular Weight: 208.27500
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-02-24 00:10:57
  • Modify Date: 2024-01-10 08:01:42
  • S-acetyl-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-triethylene glycol
Synonyms 2-(2-(2-(thioacetyl)ethoxy)ethoxy) ethanol
3,6-dioxanon-8-ethylthioacetyl-1-ol
Description S-acetyl-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H16O4S
Molecular Weight 208.27500
Exact Mass 208.07700
PSA 81.06000
LogP 0.29160