1421933-33-6

1421933-33-6 structure
1421933-33-6 structure
  • Name: S-Acetyl-PEG3-C2-acid
  • Chemical Name: S-acetyl-PEG3-acid
  • CAS Number: 1421933-33-6
  • Molecular Formula: C11H20O6S
  • Molecular Weight: 280.338
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-30 09:58:44
  • Modify Date: 2024-01-21 02:20:05
  • S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-PEG3-acid
Synonyms 6,9,12-Trioxa-3-thiapentadecan-15-oic acid, 2-oxo-
2-Oxo-6,9,12-trioxa-3-thiapentadecan-15-oic acid
MFCD22574765
Description S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 421.4±40.0 °C at 760 mmHg
Molecular Formula C11H20O6S
Molecular Weight 280.338
Flash Point 208.7±27.3 °C
Exact Mass 280.098053
LogP -0.17
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.489