40632-21-1

40632-21-1 structure
40632-21-1 structure

Name Uridine-5,6-d2
Synonyms 5,6-dideuterio-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Description Uridine-d2-1 is the deuterium labeled Uridine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Density 1.689g/cm3
Melting Point 162-164ºC
Molecular Formula C9H10D2N2O6
Molecular Weight 246.21400
Exact Mass 246.08200
PSA 124.78000
Index of Refraction 1.643

~99%

40632-21-1 structure

40632-21-1

Literature: Esaki, Hiroyoshi; Aoki, Fumiyo; Maegawa, Tomohiro; Hirota, Kosaku; Sajiki, Hironao Heterocycles, 2005 , vol. 66, # 1 p. 361 - 369
Precursor  1

DownStream  0