208518-52-9

208518-52-9 structure

Name: Epothilone F
Chemical Name: Epothilone F
CAS Number: 208518-52-9
Molecular Formula: C₂₇H₄₁NO₇S
Molecular Weight: 523.68200
Catalog: API Antineoplastic agents Natural source antineoplastic agents
Create Date: 2018-01-14 09:46:09
Modify Date: 2024-01-05 12:53:19
Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells, drug-resistant ovarian cancer cells[1].

Name	Epothilone F
Synonyms	epothilone F (1S,3S(E),7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione (1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-3-[(E)-2-(2-hydroxymethyl-thiazol-4-yl)-1-methyl-vinyl]-8,8,10,12,16-pentamethyl-4,17-dioxa-bicyclo[14.1.0]heptadecane-5,9-dione

Description	Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells, drug-resistant ovarian cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Flörsheimer A, et al. Epothilones and their analogues-a new class of promising microtubule inhibitors[J]. Expert Opinion on Therapeutic Patents, 2001, 11(6): 951-968.