1219804-22-4

1219804-22-4 structure
1219804-22-4 structure
  • Name: Hexazinone-d6
  • Chemical Name: 6-{Bis[(2H3)methyl]amino}-3-cyclohexyl-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
  • CAS Number: 1219804-22-4
  • Molecular Formula: C12H14D6N4O2
  • Molecular Weight: 258.350
  • Catalog: Research Areas Infection
  • Create Date: 2018-01-30 19:21:28
  • Modify Date: 2024-01-20 19:28:53
  • Hexazinone-d6 is the deuterium labeled Hexazinone[1]. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[2].

Name 6-{Bis[(2H3)methyl]amino}-3-cyclohexyl-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
Synonyms 6-{Bis[(H)methyl]amino}-3-cyclohexyl-1-methyl-1,3,5-triazine-2,4(1H,3H)-dione
1,3,5-Triazine-2,4(1H,3H)-dione, 3-cyclohexyl-6-(dimethyl-d-amino)-1-methyl-
Description Hexazinone-d6 is the deuterium labeled Hexazinone[1]. Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Hexazinone.From Wikipedia

Density 1.3±0.1 g/cm3
Boiling Point 332.8±25.0 °C at 760 mmHg
Molecular Formula C12H14D6N4O2
Molecular Weight 258.350
Flash Point 155.1±23.2 °C
Exact Mass 258.196289
LogP 1.85
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.612