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179986-93-7

179986-93-7 structure
179986-93-7 structure

Name (Pro34)-Peptide YY (huMan)
Synonyms YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRPRY-NH2
Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Pro-Arg-Tyr-NH2
Description (Pro34)-Peptide YY (human) is a highly Y1-selective full agonist of Peptide YY (HY-P1514)/neuropeptide Y receptors[1].
Related Catalog
Target

NPY Y1 receptor

In Vitro (Pro34)-Peptide YY (human) 在完整的 SK-N-MC 和 HEL 细胞 (Y1 样亚型) 和猪脾膜 (Y2 样亚型) 中竞争所有特定的 [125I] 神经肽 Y 结合位点。(Pro34)-Peptide YY 在完整的 SK-N-MC 和 HEL 细胞中的亲和力 (pKi 分别为 7.8 ± 0.2 和 8.2 ± 0.1) 与 Peptide YY (pKi 分别为 8.5 ± 0.1 和 8.6 ± 0.1) 非常相似[1]。
References

[1]. Grandt D, et al. [Pro34]peptide YY is a Y1-selective agonist at peptide YY/neuropeptide Y receptors. Eur J Pharmacol. 1994 Oct 14;269(2):127-32.  

Molecular Formula C194H294N54O56