1951408-58-4
1951408-58-4 structure
- Name: MAK683
- Chemical Name: MAK683
- CAS Number: 1951408-58-4
- Molecular Formula: C20H17FN6O
- Molecular Weight: 376.39
- Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
- Create Date: 2018-05-21 08:00:00
- Modify Date: 2024-01-11 12:08:30
-
EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.
| Name | MAK683 |
|---|---|
| Synonyms | EED inhibitor-1 |
| Description | EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay. |
|---|---|
| Related Catalog | |
| Target |
IC50: 59 nM (EED Alphascreen), 89 nM (LC-MS), 26 nM (ELISA)[1] |
| In Vitro | EED inhibitor-1 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1]. |
| References |
[1]. US20160176882 A1 |
| Molecular Formula | C20H17FN6O |
|---|---|
| Molecular Weight | 376.39 |
| Storage condition | 2-8℃ |