1263373-43-8
1263373-43-8 structure
- Name: NVP 2
- Chemical Name: NVP-2
- CAS Number: 1263373-43-8
- Molecular Formula: C27H37ClN6O2
- Molecular Weight: 513.075
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2018-06-03 04:09:25
- Modify Date: 2024-01-10 18:38:27
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NVP-2 is a CDK9 inhibitor with an IC50 of 0.5 nM.
| Name | NVP-2 |
|---|---|
| Synonyms |
2H-Pyran-4-carbonitrile, 4-[[[5'-chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-
4-[({5'-Chloro-2'-[(trans-4-{[(2R)-1-methoxy-2-propanyl]amino}cyclohexyl)amino]-2,4'-bipyridin-6-yl}amino)methyl]tetrahydro-2H-pyran-4-carbonitrile NVP-2 |
| Description | NVP-2 is a CDK9 inhibitor with an IC50 of 0.5 nM. |
|---|---|
| Related Catalog | |
| Target |
CDK9:0.5 nM (IC50) |
| References |
[1]. Wang J, et al. SnapShot: Kinase Inhibitors I. Mol Cell. 2015 May 21;58(4):708.e1. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 704.5±60.0 °C at 760 mmHg |
| Molecular Formula | C27H37ClN6O2 |
| Molecular Weight | 513.075 |
| Flash Point | 379.9±32.9 °C |
| Exact Mass | 512.266663 |
| LogP | 3.28 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.594 |
| Storage condition | 2-8℃ |