672926-33-9

672926-33-9 structure

Name: Kif15-IN-2
Chemical Name: Kif15-IN-2
CAS Number: 672926-33-9
Molecular Formula: C₂₀H₂₀N₆O₄S
Molecular Weight: 440.476
Catalog: Signaling Pathways Cell Cycle/DNA Damage Kinesin
Create Date: 2018-06-26 01:24:00
Modify Date: 2024-04-02 17:29:28
Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.

Name	Kif15-IN-2
Synonyms	3(2H)-Quinazolineacetamide, 1,4-dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-, (αS)- (2S)-2-(2,4-Dioxo-1,4-dihydro-3(2H)-quinazolinyl)-3-methyl-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-1,3-thiazol-2-yl]butanamide

Description	Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Kinesin Signaling Pathways >> Cytoskeleton >> Kinesin Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Research Areas >> Cancer
Target	KIF15
In Vitro	Kif15-IN-2 (Compound 14) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation[1].
References	[1]. Quinazolinedione derivatives useful for treating cellular proliferative disorders and disorders associated with Kif15 kinesin activity are described. US 20040053948 A1.