115621-84-6

115621-84-6 structure
115621-84-6 structure
  • Name: PAF-AN-1
  • Chemical Name: PAF-AN-1
  • CAS Number: 115621-84-6
  • Molecular Formula: C28H28N2O3
  • Molecular Weight: 440.53
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-02-27 23:46:42
  • Modify Date: 2024-01-16 11:33:55
  • PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

Name PAF-AN-1
Description PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.
Related Catalog
In Vitro PAF-AN-1 is extracted from patent EP0469477A1, page 2, line 47[1]. PAF-AN-1 is a 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline analog. PAF-AN-1 inhibits PAF-induced bronchoconstriction and hemoconcentration when administered po to the guinea pig[2].
References

[1]. EP0469477A1

[2]. Houlihan WJ, et al. Structural modification of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinoline platelet activating factor receptor antagonists. J Med Chem. 1993 Oct 15;36(21):3098-102.

Molecular Formula C28H28N2O3
Molecular Weight 440.53