2070018-30-1

2070018-30-1 structure

Name: IDO-IN-3
Chemical Name: IDO-IN-3
CAS Number: 2070018-30-1
Molecular Formula: C₁₁H₁₂BrFN₆O₂
Molecular Weight: 359.15
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2018-03-19 00:28:48
Modify Date: 2024-02-18 20:15:16
IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.

Name	IDO-IN-3

Description	IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Cancer
Target	IDO:290 nM (IC50) IDO:98 nM (IC50, in HeLa cell)
In Vitro	IDO-IN-3 (Compound 4c) is a potent (HeLa IC50=98 nM) inhibitor of IDO[1].
References	[1]. Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491.