151294-96-1

151294-96-1 structure

Name: Biotin-C4-amide-C5-NH2
Chemical Name: N-(4-Aminobutyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
CAS Number: 151294-96-1
Molecular Formula: C₁₄H₂₆N₄O₂S
Molecular Weight: 314.447
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-06-13 00:33:25
Modify Date: 2024-01-10 18:17:35
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	N-(4-Aminobutyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Synonyms	1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(4-aminobutyl)hexahydro-2-oxo- N-(4-Aminobutyl)-5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide Biotin-C4-amide-C5-NH2

Description	Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.