Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GABAA receptor agent 1
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

DC Chemicals Limited
China
Product Name: Ppk1-in-8
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao

1571-87-5

1571-87-5 structure

1571-87-5 structure

Name: GABAA receptor agent 1
Chemical Name: 2-(4-Chlorophenyl)-6-nitro-1H-benzimidazole
CAS Number: 1571-87-5
Molecular Formula: C₁₃H₈ClN₃O₂
Molecular Weight: 273.674
Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
Create Date: 2018-07-04 06:33:11
Modify Date: 2024-04-03 20:07:47
GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1].

Name	2-(4-Chlorophenyl)-6-nitro-1H-benzimidazole
Synonyms	2-(4-Chlorophenyl)-6-nitro-1H-benzimidazole MFCD05256114 MFCD00616523 1H-Benzimidazole, 2-(4-chlorophenyl)-6-nitro-

Description	GABAA receptor agent 1 is a high affinity ligand for GABAA receptor, with potent anticonvulsant activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor
In Vivo	GABAA receptor agent 1 (30 mg/kg; intraperitoneal) inhibits the maximum electroshock (MES) and pentylenetetrazole (PTZ)-induced convulsions in swiss albino rats[1].
References	[1]. Jain P, et al. Design, synthesis and biological evaluation of some novel benzimidazole derivatives for their potential anticonvulsant activity. Arch Pharm Res. 2010 Jul;33(7):971-80.

Density	1.5±0.1 g/cm3
Boiling Point	502.1±56.0 °C at 760 mmHg
Molecular Formula	C₁₃H₈ClN₃O₂
Molecular Weight	273.674
Flash Point	257.5±31.8 °C
Exact Mass	273.030518
LogP	3.21
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.719

Hazard Codes	Xi