440327-45-7

440327-45-7 structure

Name: 3’-O-Levulinyl-2’-deoxyadenosine
Chemical Name: 2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine
CAS Number: 440327-45-7
Molecular Formula: C₁₅H₁₉N₅O₅
Molecular Weight: 349.34
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-06 16:24:02
Modify Date: 2024-01-09 13:32:25
3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine
Synonyms	Adenosine, 2'-deoxy-3'-O-(1,4-dioxopentyl)- 2'-Deoxy-3'-O-(4-oxopentanoyl)adenosine

Description	3’-O-Levulinyl-2’-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.