1334177-80-8
1334177-80-8 structure
- Name: Cbz-NH-PEG6-C2-acid
- Chemical Name: 3-Oxo-1-phenyl-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- CAS Number: 1334177-80-8
- Molecular Formula: C23H37NO10
- Molecular Weight: 487.541
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-11 06:46:04
- Modify Date: 2024-01-23 11:38:09
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Cbz-NH-PEG6-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-Oxo-1-phenyl-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid |
|---|---|
| Synonyms |
2,7,10,13,16,19,22-Heptaoxa-4-azapentacosan-25-oic acid, 3-oxo-1-phenyl-
3-Oxo-1-phenyl-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid |
| Description | Cbz-NH-PEG6-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 627.2±55.0 °C at 760 mmHg |
| Molecular Formula | C23H37NO10 |
| Molecular Weight | 487.541 |
| Flash Point | 333.1±31.5 °C |
| Exact Mass | 487.241760 |
| LogP | -0.25 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.503 |