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1347750-74-6

1347750-74-6 structure
1347750-74-6 structure
  • Name: Cbz-NH-PEG5-C2-acid
  • Chemical Name: Cbz-N-amido-PEG5-acid
  • CAS Number: 1347750-74-6
  • Molecular Formula: C21H33NO9
  • Molecular Weight: 443.488
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-17 03:25:17
  • Modify Date: 2024-01-04 15:00:21
  • Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Cbz-N-amido-PEG5-acid
Synonyms CBZ-N-AMIDO-PEG5-COOH
Description Cbz-NH-PEG5-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 599.4±50.0 °C at 760 mmHg
Molecular Formula C21H33NO9
Molecular Weight 443.488
Flash Point 316.3±30.1 °C
Exact Mass 443.215546
LogP 0.11
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.507