136399-05-8
136399-05-8 structure
- Name: Bromo-PEG6-alcohol
- Chemical Name: 17-Bromo-3,6,9,12,15-pentaoxaheptadecan-1-ol
- CAS Number: 136399-05-8
- Molecular Formula: C12H25BrO6
- Molecular Weight: 345.227
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-28 02:09:53
- Modify Date: 2024-01-02 20:02:11
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Bromo-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 17-Bromo-3,6,9,12,15-pentaoxaheptadecan-1-ol |
|---|---|
| Synonyms |
MFCD20926394
3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-bromo- 17-Bromo-3,6,9,12,15-pentaoxaheptadecan-1-ol |
| Description | Bromo-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 404.9±40.0 °C at 760 mmHg |
| Molecular Formula | C12H25BrO6 |
| Molecular Weight | 345.227 |
| Flash Point | 198.7±27.3 °C |
| Exact Mass | 344.083435 |
| LogP | -1.25 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.474 |