1374658-84-0
1374658-84-0 structure
- Name: Propargyl-PEG3-Boc
- Chemical Name: 2-Methyl-2-propanyl 3-{2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy}propanoate
- CAS Number: 1374658-84-0
- Molecular Formula: C14H24O5
- Molecular Weight: 272.337
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-15 06:43:23
- Modify Date: 2024-08-10 09:37:13
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Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-Methyl-2-propanyl 3-{2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy}propanoate |
|---|---|
| Synonyms |
MFCD22201522
Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 3-{2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy}propanoate Propargyl-PEG3-t-butyl ester |
| Description | Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 337.2±27.0 °C at 760 mmHg |
| Molecular Formula | C14H24O5 |
| Molecular Weight | 272.337 |
| Flash Point | 143.3±23.8 °C |
| Exact Mass | 272.162384 |
| LogP | 1.25 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.452 |