2055024-44-5

2055024-44-5 structure
2055024-44-5 structure
  • Name: Propargyl-peg3-sulfone-peg3-propargyl
  • Chemical Name: Propargyl-peg3-sulfone-peg3-propargyl
  • CAS Number: 2055024-44-5
  • Molecular Formula: C22H38O10S
  • Molecular Weight: 494.60
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:43:10
  • Modify Date: 2024-01-16 16:09:38
  • Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-peg3-sulfone-peg3-propargyl
Synonyms MFCD30182062
Description Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H38O10S
Molecular Weight 494.60