1446282-42-3
1446282-42-3 structure
- Name: Bis-PEG4-TFP ester
- Chemical Name: Bis(2,3,5,6-tetrafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
- CAS Number: 1446282-42-3
- Molecular Formula: C24H22F8O8
- Molecular Weight: 590.414
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-21 22:49:26
- Modify Date: 2024-01-15 14:30:50
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Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Bis(2,3,5,6-tetrafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate |
|---|---|
| Synonyms |
Bis(2,3,5,6-tetrafluorophenyl) 4,7,10,13-tetraoxahexadecane-1,16-dioate
4,7,10,13-Tetraoxahexadecane-1,16-dioic acid, bis(2,3,5,6-tetrafluorophenyl) ester |
| Description | Bis-PEG4-TFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 572.7±50.0 °C at 760 mmHg |
| Molecular Formula | C24H22F8O8 |
| Molecular Weight | 590.414 |
| Flash Point | 289.0±25.0 °C |
| Exact Mass | 590.118713 |
| LogP | 3.76 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.474 |