35683-17-1

35683-17-1 structure

Name: Dihydrobaicalein
Chemical Name: (2S)-5,6,7-Trihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
CAS Number: 35683-17-1
Molecular Formula: C₁₅H₁₂O₅
Molecular Weight: 272.25
Create Date: 2018-07-11 16:41:19
Modify Date: 2024-01-09 14:25:20
Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].

Name	(2S)-5,6,7-Trihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Synonyms	4H-1-Benzopyran-4-one, 2,3-dihydro-5,6,7-trihydroxy-2-phenyl-, (2S)- (2S)-5,6,7-Trihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

Description	Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Polo-like Kinase (PLK)
Target	PLK1
References	[1]. Woo SU, et al. 7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells. Planta Med. 2019 Feb;85(3):217-224.