Dihydrobaicalein

Modify Date: 2024-01-09 14:25:20

Dihydrobaicalein Structure
Dihydrobaicalein structure
Common Name Dihydrobaicalein
CAS Number 35683-17-1 Molecular Weight 272.25
Density 1.5±0.1 g/cm3 Boiling Point 595.0±50.0 °C at 760 mmHg
Molecular Formula C15H12O5 Melting Point N/A
MSDS N/A Flash Point 231.7±23.6 °C

 Use of Dihydrobaicalein


Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].

 Names

Name (2S)-5,6,7-Trihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Synonym More Synonyms

 Dihydrobaicalein Biological Activity

Description Dihydrobaicalein is a PLK1 Inhibitor with an IC50 of 6.3 μM. Dihydrobaicalein also inhibits VRK2 and PLK2. Dihydrobaicalein is a natural product that can be isolated from Scutellaria scandens[1].
Related Catalog
Target

PLK1

References

[1]. Woo SU, et al. 7-O-Methylwogonin from Scutellaria baicalensis Disturbs Mitotic Progression by Inhibiting Plk1 Activity in Hep3B Cells. Planta Med. 2019 Feb;85(3):217-224.  

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 595.0±50.0 °C at 760 mmHg
Molecular Formula C15H12O5
Molecular Weight 272.25
Flash Point 231.7±23.6 °C
Exact Mass 272.068481
LogP 3.83
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.693

 Synonyms

4H-1-Benzopyran-4-one, 2,3-dihydro-5,6,7-trihydroxy-2-phenyl-, (2S)-
(2S)-5,6,7-Trihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one