111768-16-2

111768-16-2 structure
111768-16-2 structure
  • Name: Demethoxyfumitremorgin C
  • Chemical Name: demethoxyfumitremorgin C
  • CAS Number: 111768-16-2
  • Molecular Formula: C21H23N3O2
  • Molecular Weight: 349.43
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-06-05 07:05:36
  • Modify Date: 2024-01-15 11:02:37
  • Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage[1].

Name demethoxyfumitremorgin C
Synonyms 5H,14H-Pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione, 1,2,3,5a,6,11,12,14a-octahydro-12-(2-methyl-1-propen-1-yl)-, (5aS,12S,14aS)-
demethoxyfumitremorgin C
(5aS,12S,14aS)-12-(2-Methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
Description Demethoxyfumitremorgin C is a secondary metabolite of the marine fungus, Aspergillus fumigatus. Demethoxyfumitremorgin C induces prostate cancer cell apoptosis. Demethoxyfumitremorgin C activates caspase-3, -8, and -9, leading to PARP/ cleavage[1].
Related Catalog
References

[1]. Kim YS, et al. Apoptotic effect of demethoxyfumitremorgin C from marine fungus Aspergillus fumigatus on PC3 human prostate cancer cells. Chem Biol Interact. 2017 May 1;269:18-24.  

Density 1.3±0.1 g/cm3
Boiling Point 617.8±55.0 °C at 760 mmHg
Molecular Formula C21H23N3O2
Molecular Weight 349.43
Flash Point 327.4±31.5 °C
Exact Mass 349.179016
LogP 1.89
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.692
Storage condition 2-8℃
Hazard Codes Xi