225523-86-4

225523-86-4 structure

Name: Azido-PEG7-azide
Chemical Name: 1,23-Diazido-3,6,9,12,15,18,21-heptaoxatricosane
CAS Number: 225523-86-4
Molecular Formula: C₁₆H₃₂N₆O₇
Molecular Weight: 420.461
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-01 03:05:55
Modify Date: 2024-01-09 19:38:19
Azido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,23-Diazido-3,6,9,12,15,18,21-heptaoxatricosane
Synonyms	3,6,9,12,15,18,21-Heptaoxatricosane, 1,23-diazido- 1,23-Diazido-3,6,9,12,15,18,21-heptaoxatricosane

Description	Azido-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.