1374666-32-6
1374666-32-6 structure
- Name: Mal-PEG2-acid
- Chemical Name: 3-{2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoic acid
- CAS Number: 1374666-32-6
- Molecular Formula: C11H15NO6
- Molecular Weight: 257.240
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-06-28 01:56:23
- Modify Date: 2024-01-06 10:23:03
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Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1].
| Name | 3-{2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoic acid |
|---|---|
| Synonyms |
3-{2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoic acid
Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]- |
| Description | Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 455.7±35.0 °C at 760 mmHg |
| Molecular Formula | C11H15NO6 |
| Molecular Weight | 257.240 |
| Flash Point | 229.4±25.9 °C |
| Exact Mass | 257.089935 |
| LogP | -0.73 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.526 |
| Storage condition | -20°C |
| Hazard Codes | Xi |
|---|