660843-23-2
660843-23-2 structure
- Name: Mal-PEG2-NH2 TFA
- Chemical Name: 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]pyrrole-2,5-dione,2,2,2-trifluoroacetic acid
- CAS Number: 660843-23-2
- Molecular Formula: C12H17F3N2O6
- Molecular Weight: 342.26800
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-05-13 04:50:04
- Modify Date: 2024-01-11 05:07:32
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Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]pyrrole-2,5-dione,2,2,2-trifluoroacetic acid |
|---|---|
| Synonyms |
O-(2-Aminoethyl)-O inverted exclamation marka-(2-maleimidoethyl)ethylene glycol trifluoroacetate salt
O-(2-aminoethyl)-O'-(2-maleimidoethyl)ethylene glycol trifluoroacetate salt 1-[2-[2-(2-Aminoethoxy)ethoxy]ethyl]-1H-pyrrole-2,5-dione trifluoroacetate salt |
| Description | Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C12H17F3N2O6 |
|---|---|
| Molecular Weight | 342.26800 |
| Exact Mass | 342.10400 |
| PSA | 119.16000 |
| LogP | 0.17480 |
| Precursor 8 | |
|---|---|
| DownStream 0 | |