2512227-13-1

2512227-13-1 structure
2512227-13-1 structure
  • Name: Mal-PEG4-C2-NH2 TFA
  • Chemical Name: Mal-PEG4-C2-NH2 TFA
  • CAS Number: 2512227-13-1
  • Molecular Formula: C16H25F3N2O8
  • Molecular Weight: 430.37
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-13 12:38:56
  • Modify Date: 2024-01-10 18:12:56
  • Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG4-C2-NH2 TFA
Description Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H25F3N2O8
Molecular Weight 430.37
Hazard Codes Xi