144942-89-2
144942-89-2 structure
- Name: Amino-PEG1-C2-acid
- Chemical Name: 3-(2-Aminoethoxy)propanoic acid
- CAS Number: 144942-89-2
- Molecular Formula: C5H11NO3
- Molecular Weight: 133.146
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-06-26 01:46:46
- Modify Date: 2024-01-13 14:23:37
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Amino-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-(2-Aminoethoxy)propanoic acid |
|---|---|
| Synonyms |
MFCD22017475
Propanoic acid, 3-(2-aminoethoxy)- 3-(2-Aminoethoxy)propanoic acid Amino-PEG1-acid |
| Description | Amino-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 284.7±20.0 °C at 760 mmHg |
| Molecular Formula | C5H11NO3 |
| Molecular Weight | 133.146 |
| Flash Point | 126.0±21.8 °C |
| Exact Mass | 133.073898 |
| LogP | -0.85 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.466 |