1283658-71-8

1283658-71-8 structure
1283658-71-8 structure
  • Name: Methylamino-PEG4-acid HCl
  • Chemical Name: Methylamino-PEG4-acid
  • CAS Number: 1283658-71-8
  • Molecular Formula: C12H25NO6
  • Molecular Weight: 279.330
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-30 11:47:45
  • Modify Date: 2024-01-07 07:16:34
  • Methylamino-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methylamino-PEG4-acid
Synonyms 5,8,11,14-Tetraoxa-2-azaheptadecan-17-oic acid
MFCD28064328
Description Methylamino-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 405.5±40.0 °C at 760 mmHg
Molecular Formula C12H25NO6
Molecular Weight 279.330
Flash Point 199.1±27.3 °C
Exact Mass 279.168182
LogP -1.62
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.458