1355197-57-7

1355197-57-7 structure

Name: Methylamino-PEG3-azide
Chemical Name: Methylamino-PEG3-azide
CAS Number: 1355197-57-7
Molecular Formula: C₉H₂₀N₄O₃
Molecular Weight: 232.280
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-05 15:20:44
Modify Date: 2024-01-10 13:59:27
Methylamino-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methylamino-PEG3-azide
Synonyms	2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}-N-methylethanamine Ethanamine, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-N-methyl- MFCD29042356

Description	Methylamino-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562