82217-01-4

82217-01-4 structure

Name: m-PEG8-Tos
Chemical Name: m-PEG9-Tos
CAS Number: 82217-01-4
Molecular Formula: C₂₄H₄₂O₁₁S
Molecular Weight: 538.65
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-11 12:59:36
Modify Date: 2024-01-09 11:23:26
Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

Name	m-PEG9-Tos

Description	Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A.